Small Cell Lung Carcinoma (SCLC)

Small Cell Lung Carcinoma (SCLC)

Small Cell Lung Carcinoma is a highly aggressive and rapidly spreading form of lung cancer that originates from neuroendocrine cells in the lung. It accounts for about 10 -15% of all lung cancers and is strongly associated with cigarette smoking – almost all the patients with SCLC are current or former smokers. It is known for its fast growth, and it often spreads to the brain, bones, liver and adrenal glands before it is diagnosed, which makes the early detection difficult. Due to this aggressive nature, SCLC is usually diagnosed in the extensive stage rather than the limited stage.

There’re two stages in SCLC:

  1. Limited – stage: In this the cancer is confined to one lung and nearby lymph nodes.
  2. Extensive – stage: In this the cancer has spread beyond the lungs.

Symptoms of the SCLC

Causes of SCLC

Diagnosis

It can be diagnosed by:

Treatment

Frequently Asked Questions (FAQs)

It is not treated with surgery because SCLC spreads very quickly and is usually diagnosed late, surgery is rarely helpful. Chemo and radiation are the mainstays.

SCLC can double in size within weeks. That’s why early detection is rare and treatment needs to start immediately.

Yes, relapse is common. Even after a good response to the treatment, cancer often returns within 6-12 months.

Frequent scans (CT, PET, or MRI) and blood tests are done every few months and to track the response and to detect the recurrence early.

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