Biologic Therapy in Delhi | Monoclonal Antibody Treatment

Biologics/Monoclonal Antibodies

Biologics are advanced medicines made from living cells, designed to target specific parts of the immune system or disease-causing proteins. Monoclonal antibodies (mAbs) are a type of biologic engineered to bind to one specific target in the body. They are used in conditions like severe asthma, autoimmune lung diseases, and certain cancers.

Causes

Severe allergic or eosinophilic asthma not controlled by inhalers or tablets.
Chronic obstructive pulmonary disease (COPD) with frequent flare-ups linked to inflammation.
Interstitial lung disease (ILD) with an autoimmune cause.
Lung cancer or other cancers requiring targeted therapy.
Autoimmune diseases like rheumatoid arthritis or vasculitis affecting the lungs.

Symptoms

Persistent breathing difficulty despite standard treatment.
Frequent asthma or COPD exacerbations.
Severe allergic reactions triggered by environmental factors.
Worsening lung function due to immune-related inflammation.

Diagnosis

Blood tests (eosinophil count, IgE levels) to identify inflammatory markers.
Allergy testing for specific triggers.
Pulmonary function tests to assess lung capacity.
Imaging (CT scan/X-ray) to detect inflammation or damage.
Biopsy in certain autoimmune or cancer cases.

Treatment

Administration: Usually given as an injection under the skin (subcutaneous) or through a vein (intravenous) at regular intervals (every 2–8 weeks depending on the drug)
Common examples in lung care:
Omalizumab – for allergic asthma
Mepolizumab / Benralizumab – for eosinophilic asthma
Nivolumab / Pembrolizumab – for certain lung cancers
Duration: Often long-term, reviewed periodically by your doctor
Always given under medical supervision to monitor for reactions

How to prepare for the test?

Share your full medical history, including infections and vaccination status.
Inform your doctor if you are pregnant or breastfeeding.
Avoid live vaccines during treatment unless approved by your doctor.
Have baseline tests done before starting therapy.

Frequently Asked Questions (FAQs)

1. Are biologics the same as steroids?

No. Biologics target specific immune pathways, while steroids suppress the immune system broadly.

2. How soon will I see improvement?

Some people notice benefits within weeks, while for others it may take several months.

3. Do biologics cure my disease?

They control symptoms and slow disease progression but are not a permanent cure.

4. Can I stop once I feel better?

Stopping without medical advice can cause symptoms to return or worsen.